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Jung-Il Chae Selected Research

licochalcone B

8/2020Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growth.
10/2019Licochalcone B inhibits growth and induces apoptosis of human non-small-cell lung cancer cells by dual targeting of EGFR and MET.
12/2017Natural Compound Licochalcone B Induced Extrinsic and Intrinsic Apoptosis in Human Skin Melanoma (A375) and Squamous Cell Carcinoma (A431) Cells.
4/2016Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways.

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Jung-Il Chae Research Topics

Disease

33Neoplasms (Cancer)
11/2021 - 10/2008
12Squamous Cell Carcinoma of Head and Neck
01/2019 - 10/2013
8Lung Neoplasms (Lung Cancer)
01/2022 - 05/2010
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2021 - 01/2015
6Esophageal Squamous Cell Carcinoma
09/2020 - 11/2019
6Mouth Neoplasms (Oral Cancer)
05/2018 - 01/2014
5Malignant Mesothelioma
07/2016 - 06/2012
4Colorectal Neoplasms (Colorectal Cancer)
12/2021 - 01/2017
4Melanoma (Melanoma, Malignant)
09/2020 - 06/2015
3Skin Neoplasms (Skin Cancer)
01/2022 - 12/2017
3Neoplasm Metastasis (Metastasis)
06/2019 - 04/2016
3Leukemia
10/2012 - 10/2008
2Esophageal Neoplasms (Esophageal Cancer)
06/2021 - 05/2020
2Inflammation (Inflammations)
04/2021 - 01/2015
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2020 - 12/2017
2Mesothelioma
06/2013 - 06/2012
1Adenocarcinoma of Lung
01/2022
1Disease Progression
01/2022
1Human Influenza (Influenza)
06/2021
1Hypersensitivity (Allergy)
06/2021
1Thymoma (Thymic Carcinoma)
09/2020
1Glaucoma
06/2019
1Ocular Hypertension (Glaucoma, Suspect)
06/2019
1Colonic Neoplasms (Colon Cancer)
04/2018
1Breast Neoplasms (Breast Cancer)
12/2017
1Neoplastic Cell Transformation
03/2017
1Hepatocellular Carcinoma (Hepatoma)
02/2015
1Carcinoma (Carcinomatosis)
01/2015
1Chronic Kidney Failure (Chronic Renal Failure)
08/2014

Drug/Important Bio-Agent (IBA)

24Proteins (Proteins, Gene)FDA Link
06/2019 - 05/2010
11Pharmaceutical PreparationsIBA
04/2021 - 10/2013
7AntioxidantsIBA
05/2020 - 09/2013
5p38 Mitogen-Activated Protein KinasesIBA
12/2021 - 05/2018
5CaspasesIBA
06/2021 - 10/2008
5Gefitinib (Iressa)FDA Link
04/2021 - 10/2019
4licochalcone BIBA
08/2020 - 04/2016
4esculetinIBA
01/2017 - 01/2015
4SurvivinIBA
01/2014 - 06/2012
3ErbB Receptors (EGF Receptor)IBA
01/2022 - 10/2019
3Podophyllotoxin (Condylox)FDA LinkGeneric
11/2021 - 06/2020
3LignansIBA
11/2021 - 09/2020
3Tyrosine Kinase InhibitorsIBA
01/2021 - 10/2019
3licochalcone CIBA
05/2020 - 12/2018
3Annexin A5IBA
01/2020 - 12/2017
3licochalcone AIBA
12/2017 - 08/2014
3Sp1 Transcription FactorIBA
01/2017 - 10/2012
3kahweolIBA
12/2016 - 06/2012
3coumarinIBA
05/2016 - 01/2015
3beta-lapachoneIBA
02/2016 - 01/2015
3honokiolIBA
01/2015 - 06/2013
3Cyclin D1IBA
01/2014 - 06/2012
2licochalcone HIBA
01/2022 - 03/2020
2Matrix Metalloproteinases (MMPs)IBA
06/2021 - 01/2020
2deoxypodophyllotoxinIBA
04/2021 - 09/2020
2FlavonoidsIBA
05/2020 - 09/2013
2echinatinIBA
02/2020 - 11/2019
2Phosphotransferases (Kinase)IBA
01/2020 - 10/2008
2licochalcone DIBA
01/2020 - 01/2019
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020 - 05/2018
2DiterpenesIBA
12/2016 - 06/2012
2manumycinIBA
07/2016 - 11/2015
2QuercetinIBA
02/2015 - 10/2012
2CoffeeFDA Link
12/2014 - 06/2012
2Caspase 3 (Caspase-3)IBA
06/2013 - 05/2013
2epigallocatechin gallate (epigallocatechin-3-gallate)IBA
05/2010 - 10/2008
1Cell-Free Nucleic AcidsIBA
01/2022
1Epithelial Cell Adhesion MoleculeIBA
01/2022
13-deoxysappanchalconeIBA
06/2021
1Stratospheric OzoneIBA
09/2020
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
09/2020
1Janus Kinase 2IBA
08/2020
1Sinopodophyllum hexandrum extractIBA
06/2020
1PhytochemicalsIBA
05/2020
1thiazolyl blueIBA
01/2020
1netarsudilIBA
06/2019
1Actin Depolymerizing Factors (Cofilins)IBA
06/2019
1Propidium (Propidium Iodide)IBA
01/2019
1Janus KinasesIBA
01/2019
1Oxygen (Dioxygen)IBA
05/2018
1oridoninIBA
05/2018
1AgarIBA
05/2018
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2018
1CarcinogensIBA
04/2018
1Benzo(a)pyreneIBA
03/2018
1Glycoproteins (Glycoprotein)IBA
12/2017
1Cadherins (E-Cadherin)IBA
12/2017
1Indicators and Reagents (Reagents)IBA
12/2017
1Small Interfering RNA (siRNA)IBA
12/2017
1Biological ProductsIBA
12/2017
1rheinIBA
03/2017
1Epidermal Growth Factor (EGF)IBA
01/2017
14-O-methylhonokiolIBA
07/2015
1CoumarinsIBA
06/2015
16,7-dihydroxyflavoneIBA
02/2015
1quinone (benzoquinone)IBA
01/2015
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2015

Therapy/Procedure

10Therapeutics
09/2020 - 06/2012
1Complementary Therapies (Alternative Medicine)
05/2020
1Drug Therapy (Chemotherapy)
05/2020
1Organ Transplantation
08/2014